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Wirksamkeit alkoholischer Händedesinfektion


Physician staffing patterns and clinical outcomes in critically ill patients: a systematic review.

Pronovost PJ, Angus DC, Dorman T, et al.                                                                                                                          JAMA 2002; 288:2151-62

Department of Critical Care Medicine, Johns Hopkins University, Baltimore, Md, USA.

CONTEXT: Intensive care unit (ICU) physician staffing varies widely, and its association with patient outcomes remains unclear.
OBJECTIVE: To evaluate the association between ICU physician staffing and patient outcomes.
DATA SOURCE: We searched MEDLINE (January 1, 1965, through September 30, 2001) for the following medical subject heading (MeSH) terms: intensive care units, ICU, health resources/utilization, hospitalization, medical staff, hospital organization and administration, personnel staffing and scheduling, length of stay, and LOS. We also used the following text words: staffing, intensivist, critical, care, and specialist. To identify observational studies, we added the MeSH terms case-control study and retrospective study. Although we searched for non-English-language citations, we reviewed only English-language articles. We also searched EMBASE, HealthStar (Health Services, Technology, Administration, and Research), and HSRPROJ (Health Services Research Projects in Progress) via Internet Grateful Med and The Cochrane Library and hand searched abstract proceedings from intensive care national scientific meetings (January 1, 1994, through December 31, 2001).
STUDY SELECTION: We selected randomized and observational controlled trials of critically ill adults or children. Studies examined ICU attending physician staffing strategies and the outcomes of hospital and ICU mortality and length of stay (LOS). Studies were selected and critiqued by 2 reviewers. We reviewed 2590 abstracts and identified 26 relevant observational studies (of which 1 included 2 comparisons), resulting in 27 comparisons of alternative staffing strategies. Twenty studies focused on a single ICU.
DATA SYNTHESIS: We grouped ICU physician staffing into low-intensity (no intensivist or elective intensivist consultation) or high-intensity (mandatory intensivist consultation or closed ICU [all care directed by intensivist]) groups. High-intensity staffing was associated with lower hospital mortality in 16 of 17 studies (94%) and with a pooled estimate of the relative risk for hospital mortality of 0.71 (95% confidence interval [CI], 0.62-0.82). High-intensity staffing was associated with a lower ICU mortality in 14 of 15 studies (93%) and with a pooled estimate of the relative risk for ICU mortality of 0.61 (95% CI, 0.50-0.75). High-intensity staffing reduced hospital LOS in 10 of 13 studies and reduced ICU LOS in 14 of 18 studies without case-mix adjustment. High-intensity staffing was associated with reduced hospital LOS in 2 of 4 studies and ICU LOS in both studies that adjusted for case mix. No study found increased LOS with high-intensity staffing after case-mix adjustment.
CONCLUSIONS: High-intensity vs low-intensity ICU physician staffing is associated with reduced hospital and ICU mortality and hospital and ICU LOS.


Die alkoholische Händedesinfektion hat in Mitteleuropa eine lange Tradition. Alkohol wirkt sicher und schnell gegen die meisten im Krankenhaus relevanten Infektionserreger und die alkoholische Händedesinfektion ist überall durchführbar, unabhängig von Waschbecken und Wasserhähnen. In den angelsächsischen Ländern und in Frankreich sah das bisher anders aus: Das Händewaschen wurde eindeutig bevorzugt, man hatte vor allem Angst davor, dass die Haut durch die Anwendung von Alkohol leiden könnte. Die vorliegende randomisierte klinische Studie ist deshalb wichtig für die weitere Durchsetzung der alkoholischen Händedesinfektion in diesen Ländern:

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