PCT – une possibilité pour le sepsis?

Serial procalcitonin predicts mortality in severe sepsis patients: Results from the multicenter procalcitonin MOnitoring SEpsis (MOSES) Study.        

Schuetz P, Birkhahn R, Sherwin R, Jones AE, Singer A, Kline JA, Runyon MS, Self WH, et al.                      Crit Care Med 2017; 45:781-789

Efficacy and safety of procalcitonin guidance in patients with suspected or confirmed sepsis: A systematic review and meta-analysis.
      
Iankova I, Thompson-Leduc P, Kirson NY, Rice B, Hey J, Krause A, Schonfeld SA, DeBrase CR, et al.        Crit Care Med 2018; 46:691-698

Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial.    
    
de Jong E, van Oers JA, Beishuizen A, Vos P, Vermeijden WJ, Haas LE, Loef BG, Dormans T, et al.        Lancet Infect Dis 2016; 16:819-827

Systematic review and meta-analysis of procalcitonin-guidance versus usual care for antimicrobial management in critically ill patients: Focus on subgroups based on antibiotic initiation, cessation, or mixed strategies.       
 
Lam SW, Bauer SR, Fowler R, Duggal A.                                                                                                               Crit Care Med 2018; 46:684-690

Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: A patient level meta-analysis.          

Schuetz P, Wirz Y, Sager R, Christ-Crain M, Stolz D, Tamm M, Bouadma L, Luyt CE, Wolff M, et al.       Lancet Infect Dis 2018; 18:95-107